The North East Texas region, including Hunt County, is a hot spot for breast cancer incidence, the second leading cause of cancer-related deaths among American women. The introduction of antiestrogen and anti-HER2 therapies has improved the clinical outcomes of breast cancer patients. However, in over half of these patients, cancer will recur and metastasize. A novel strategy is being pursued to restore the ability of the immune system to detect and eliminate cancer cells. Four critical genes have been identified that help cancer cells evade the immune system. Inhibition of these immune evading genes is expected to be more efficient in eliminating cancer cells than therapies currently available.

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